Ebook Basic Principles of Drug Discovery and Development
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Basic Principles of Drug Discovery and Development
Ebook Basic Principles of Drug Discovery and Development
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From the Back Cover
Basic Principles of Drug Discovery and Development clearly explains the fundamental principles of the drug discovery and development process from a multidisciplinary approach. This text is ideal for readers interested in a career in the pharmaceuticals industry or nonscientists seeking an understanding of how drugs reach the marketplace. This book explains the multifaceted process of identifying new therapeutic agents in the modern era and describes the input required from a host of experts such as medicinal chemists, biologists, pharmacologists, drug metabolism experts, toxicologists, and clinicians. Given the wide range of disciplines and techniques required for cutting-edge drug discovery research, it is important that scientists have a mastery of not only their own field, but also an understanding of their collaborators’ fields. In order to provide readers with an understanding of a wide range of fields, this book describes enabling technologies for a variety of disciplines that are critical to the process. High throughput screening, structure-based drug design, molecular modeling, pharmaceutical profiling, translational medicine, and many other scientific methods that have become critical to the successful development of marketable therapeutics are described. Beginning with an historical overview of drug discovery, this book educates the reader about important drug targets by class, in vitro screening methods, medicinal chemistry strategies in drug design, principles in pharmacokinetics and pharmacodynamics, animal models of disease states, clinical trial basics, and selected business aspects of the drug discovery process. Key features Provides an introduction to the drug discovery process from obtaining a lead, to testing the bioactivity, to producing the drug, and protecting the intellectual propertyWritten for anyone looking to learn about or thinking of entering the pharmaceutical industrySimply and succinctly presents how the pharmaceutical industry works
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About the Author
As an industrial medicinal chemist, Dr. Blass has experience with major pharmaceutical organizations (Wyeth, Procter & Gamble Pharmaceuticals) and small biotech operations (Fox Chase Chemical Diversity Center), which provided him with a wealth of expertise in the art of drug discovery and development (including a wide range of disease states and biological targets). His position with Temple University’s School of Pharmacy and the Moulder Center for Drug Discovery has provided him with essential experience as an educator and academic scientist. These experiences, as well as his training and expertise as a registered US patent agent, have provided him with the tools and skills necessary to bridge the gap between industrial drug discovery and academic research.
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Product details
Paperback: 580 pages
Publisher: Academic Press; 1 edition (May 11, 2015)
Language: English
ISBN-10: 012411508X
ISBN-13: 978-0124115088
Product Dimensions:
6 x 1.3 x 8.8 inches
Shipping Weight: 2.1 pounds (View shipping rates and policies)
Average Customer Review:
4.5 out of 5 stars
4 customer reviews
Amazon Best Sellers Rank:
#353,566 in Books (See Top 100 in Books)
Very comprehensive
great book for a drug discovery class
Good, readable introduction to the topic. The index would be more useful if it had a couple more entries, though. Haven't finished reading it yet, but no other complaints so far.
Very nice book!
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